Leaders in Research Peptides
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Leaders in Research Peptides
BPC-157, a pentadecapeptide derived from human gastric juice, exhibits a variety of biological effects that are beneficial in both in vitro and in vivo studies.
Firstly, BPC-157 demonstrates significant wound-healing and tissue-regenerating properties. It promotes the healing of various wounds including skin, muscle, bone, nervous tissue and is especially effective in healing damaged ligaments and tendons. It does so by inhibiting the growth of a compound called 4‐hydroxynonenal, and accelerating the rate of angiogenic repair, facilitating granulation tissue formation, and improving collagen deposition.
Secondly, BPC-157 exhibits potent anti-inflammatory effects. Studies have shown that it can counteract inflammation and oxidative stress in various tissues, which makes it a promising candidate for the treatment of inflammatory diseases.
Furthermore, BPC-157 exhibits neuroprotective effects. It has been demonstrated to attenuate serotonin syndrome and counteract various dopamine system disturbances.
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Promotion of tissue healing: BPC-157 has been shown in research to accelerate the healing of musculoskeletal soft tissues, potentially due to increased angiogenesis .
Anti-inflammatory properties: Studies suggest the peptide exhibits anti-inflammatory effects, potentially modulating the body’s inflammatory response to injury or disease .
Neuroprotective effects: One study suggested BPC-157 may counteract damage caused by paracetamol-induced convulsions and brain damage in rats .
Potential treatment for knee pain: Initial studies suggest intra-articular injection of BPC-157 may help alleviate multiple types of knee pain .
Esophagocutaneous fistula healing therapy: Application of BPC-157 may precipitate therapeutic benefits in esophagocutaneous fistula healing according to research .
Antioxidant activities: According to research, engineered Lactococcus lactis as a delivery vehicle for BPC-157 demonstrates antioxidant activity, reducing ROS production in cell models .
Cytoprotective properties: Research has demonstrated that BPC-157 may serve as a useful cytoprotective peptide therapy in heart disturbances, myocardial infarction, and heart failure .
Potential treatment for abdominal aorta anastomosis: BPC-157 shows immediate benefits when applied as a bath immediately after anastomosis .
Improved healing of esophagogastric anastomosis: Studies have shown the application of BPC-157 and L-arginine improved the healing process in rats .
While these benefits are promising, it’s important to note that most of these studies have been conducted in vitro or on animal models. Further human clinical trials are needed to confirm these benefits and determine the appropriate dosage for therapeutic use.
 https://link.springer.com/article/ 10.1007/s00441-019-03016-8
 https://link.springer.com/article/ 10.1007/s00253-018-9333-6
 https://www.ncbi.nlm.nih.gov/pmc/ articles/PMC5107594/
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