Thymosin alpha-1 (Tα1) is a 28-amino acid peptide first isolated from calf thymuses. The peptide primarily functions as an immune system modulator, augmenting T-cell response, stimulating cytokine production, and enhancing the functional activities of natural killer cells. Consequently, Thymosin alpha-1 has found use in treating diseases associated with immune dysregulation.
In oncology, Thymosin alpha-1 has exhibited potential as an adjunctive therapy, bolstering the body’s immune response against tumor cells and thereby improving the effectiveness of conventional cancer treatments.
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[1] https://www.tandfonline.com/doi/ abs/10.1080/14712598.2018.1484104
[2] https://www.sciencedirect.com/science/ article/pii/S1201971214017500
[3] https://pubmed.ncbi.nlm.nih.gov/23327199/
[4] https://www.sciencedirect.com/science/ article/abs/pii/S0083672916300036
[5] https://pubmed.ncbi.nlm.nih.gov/18534287/
[6] https://nyaspubs.onlinelibrary.wiley.com/ doi/abs/10.1196/annals.1415.044
[7] https://www.frontiersin.org/journals/ oncology/articles/10.3389/fonc.2019.00873/full
[8] https://pubmed.ncbi.nlm.nih.gov/30063864/
[9] https://www.tandfonline.com/doi/ full/10.1517/14712598.2015.1007948
[10] https://pubmed.ncbi.nlm.nih.gov/28106477/
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